Xeomin

Pure Precision. Proven Results.

Known in the industry as “naked tox,” Xeomin® stands alone as the only neuromodulator stripped of unnecessary complexing proteins—delivering only the active ingredient you need. At Applied Aesthetic in Garden City, NY, every Xeomin® treatment is administered with meticulous attention to facial anatomy and natural movement, harnessing this uniquely pure formulation for targeted wrinkle reduction that our discerning Garden City patients trust.

What Is Xeomin®?

Xeomin® is a highly purified botulinum toxin type A that stands apart from other neuromodulators through its unique manufacturing process. Unlike other injectables, Xeomin® contains no complexing proteins, earning it the distinction of being the “naked” neurotoxin. This purity means your body receives only the active ingredient necessary for smooth, natural-looking results.

Type of Treament

FDA-approved botulinum toxin used in both aesthetic medicine and therapeutic applications for treating dynamic wrinkles and various health conditions.

Results Timeline

Initial improvements are visible within 3-4 days, with full results developing over the next several weeks. Effects typically last 3-4 months.

Am I a Good Candidate for Xeomin®?

Most healthy adults are excellent candidates. We’ll discuss your medical history and aesthetic goals to ensure Xeomin® is right for you.

What Can Xeomin® Treat?

Frown lines between the eyebrows (glabellar lines)

Horizontal forehead wrinkles

Crow’s feet around the eyes

Bunny lines on the nose

Neck bands and platysmal bands

Jawline contouring (masseter reduction)

Excessive sweating (hyperhidrosis)

Muscle spasticity conditions

How It Works

Xeomin® works by temporarily blocking nerve signals to targeted facial muscles, preventing the repetitive contractions that create dynamic wrinkles. What sets Xeomin® apart is its double-filtration process, which removes complexing proteins found in other neuromodulators. This results in a pure botulinum toxin that may reduce the risk of developing resistance over time. The streamlined formulation allows for precise muscle relaxation while maintaining natural facial expression and movement.

Xeomin® Benefits: Why You'll Love It

Pure Formulation Without Additives 

The absence of complexing proteins means less risk of developing antibody resistance, potentially making Xeomin® more effective for those who have built up immunity after prolonged Botox® use. 

Natural-Looking Movement 

Precisely placed injections preserve your ability to express emotions while smoothing unwanted lines, creating results that look authentically you.

Proven Clinical Efficacy 

Extensive clinical trials demonstrate Xeomin®’s effectiveness in reducing moderate to severe frown lines with results comparable to leading competitors.

FDA-Approved for Medical Conditions

Xeomin®’s therapeutic applications include treating cervical dystonia, blepharospasm (involuntary blinking), upper limb spasticity, and chronic sialorrhea, showcasing its proven medical versatility.

Versatile Cosmetic Applications 

Beyond wrinkle reduction, Xeomin® excels at jawline slimming, brow lifting, gummy smile correction, and creating subtle facial contouring effects throughout the face.

No Downtime Required 

Most patients return to normal activities immediately after treatment, making it perfect for busy lifestyles and professional schedules.

Long-Lasting Results 

Effects typically last 3-4 months. Just like with Botox and other wrinkle relaxers, consistent treatment schedules help prevent new lines from forming while prolonging your smooth results.

What Should I Expect?

Before

We’ll start by discussing what you’d like to achieve and mapping the best approach for your unique facial structure. To help minimize any bruising, we recommend skipping blood thinners and alcohol for 24 hours beforehand.

During

We begin by applying numbing cream or ice to keep you comfortable throughout the process. The actual injections feel like a slight pinch as Xeomin® is delivered to each treatment area. The entire process takes about 10-15 minutes, and you’ll be in and out in under 30 minutes total.

After

You might notice some mild redness or slight swelling, but this typically fades within a few hours. We’ll ask you to stay upright for 4 hours and skip intense workouts for a day. Your results will gradually emerge over the next week.

Questions? We have answers!

What's the difference between Botox and Xeomin®?

While both are botulinum toxin type A, Xeomin®’s double-filtration process removes the complexing proteins present in Botox, creating a purer formulation. This “naked” approach means less foreign protein exposure, potentially reducing antibody formation that can lead to treatment resistance. For patients who’ve noticed their Botox results aren’t lasting as long as they used to, Xeomin® offers a fresh start with comparable smoothing power and the potential for renewed effectiveness.

Most patients achieve optimal results with a single treatment session. However, the number of units needed varies based on muscle strength, treatment area size, and desired outcome. Touch-up treatments may be recommended 2 weeks post-injection for fine-tuning results.

Absolutely. Xeomin® pairs beautifully with dermal fillers, laser treatments, and skincare procedures. We often recommend combining neuromodulators with volumizing treatments for comprehensive facial rejuvenation, creating both smoothness and restored fullness.

Results vary based on the individual; however, most patients will experience the effects of Xeomin® for 3-4 months. Consistency is key—patients who maintain regular treatment schedules often find their results last longer and require fewer units over time.

For the first 24 hours, avoid strenuous exercise, excessive heat exposure, and lying flat for extended periods. Skip facial massages and aggressive skincare treatments for one week. These precautions help ensure optimal product placement and results.

When administered by experienced injectors, Xeomin® creates beautifully natural results. The key is precise placement and appropriate dosing that relaxes muscles without freezing expression. You’ll look refreshed and smooth while maintaining your natural facial character.

Absolutely! Men are increasingly choosing Xeomin® and other neuromodulators—over one million botulinum toxin treatments were performed on men in just the past three years. Most men tell us they simply want to look as good as they feel and address the changes they notice in the mirror. At Applied Aesthetic, we understand masculine facial structure and adjust our injection approach accordingly for results that look authentically natural.

Discover the Naked Neurotoxin Difference

At Applied Aesthetic in Garden City, NY, every Xeomin® treatment reflects our deep expertise in facial anatomy and injection artistry. Led by Natalie Sharpe, FNP-BC, named one of the top US injectors in 2025, we’ve built our reputation on delivering beautifully natural results that enhance what’s already uniquely yours.